Scientific Director MLAS Program Director of the Institute for Laboratory Animal Science University Hospital Aachen RWTH Aachen University
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Prof. Dr. René H. Tolba is Professor and Director of the Institute for Laboratory Animal Science & Experimental Surgery, Medical Faculty RWTH Aachen University. He is also the current President of the German Society of Laboratory Animal Science (GV-SOLAS). His research focus is visceral organ transplantation and preservation, as well as animal models for various disciplines. He is responsible for training and education according to FELASA recommendations and teaching in M.Sc. in Biomedical Engineering. Additionally, the Institute has several research projects within the 3R topics and a project funded by the German Ministry for Research and Education (BMBF) for developing educational media for Laboratory Animal Research. In the session with Prof. Tolba the following topics will be taught:
Regulatory affairs needed for the registration of medical products
How to design and evaluate your experiments
Architecture and Facility Design and the implication for routine mode of the facility
Applied Anaesthesia and Analgesics Regimens -basics, advanced protocols and tips
Microsurgery -basic training and advanced skills
PD Dr. phil. nat. Julia Steitz
Scientific Co-Director MLAS Program Director of the Laboratory of Clinical Chemistry/Hematology & Microbiology Institute for Laboratory Animal Science University Hospital Aachen RWTH Aachen University
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PD Dr. phil. nat. Julia Steitz is a senior scientist and Director of the Central Laboratories of the Institute for Laboratory Animal Science, Medical Faculty RWTH Aachen University. The Central Laboratories include Hematology, Clinical Chemistry, Microbiology, and Histopathology. She is also a Principal Investigator in several research projects focusing on the development of tumor models for the analysis of novel immunotherapeutic agents. Additionally, her research activities include the analysis of efficacy, safety and toxicity of medical products and tumor therapeutics in vitro and in different in vivo animal models. PD Dr. Steitz is a lecturer in educational programs run according to FELASA recommendations and in the RWTH’s M.Sc. in Biomedical Engineering program. In the sessions with PD Dr. J. Steitz the following topics will be taught:
Regulatory Affairs in preclinical studies
How to design, perform and evaluate experiments (basic training and skills)
How to use cell culture systems to reduce, refine and replace animal experiments
Basics of Clinical Chemistry, Hematology and Molecular Biology and their methods
How to choose the right animal model
Animal models in Immunology, Oncology and Infectious Diseases
Prof. Dr. med. Dr. med.dent. Dr. phil. Dominik Groß
Director of the Institute of History, Theory and Ethics in Medicine University Hospital Aachen RWTH Aachen University
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Prof. Dr. Dr. Dr. Dominik Gross is the Director of the Institute for History, Theory and Ethics in Medicine at the RWTH Aachen University and Chairman of the Clinical Ethics Committee at Aachen University Hospital. Prof. Gross studied dentistry, history/philosophy/archaeology and medicine, completing each with a doctorate, and in 1998 received postdoctoral qualifications in history, theory and ethics in medicine. In 2005 he was appointed Chair of History, Theory and Ethics in Medicine at RWTH Aachen University. His main teaching and research areas are the professionalization of health care professions, ethical questions in clinical medicine, technology ethics and technology acceptance, as well as animal ethics. In addition to his scientific and teaching activities he is an active political consultant including for the German Federal Ministry of Health, the German Federal Ministry for Education and Research, the Institute for Quality and Efficiency in Health Care (IQWiG) and the German Medical Association. In the sessions with Prof. Gross the following topics will be addressed:
Ethics in animal experimentation
Introduction to ethics with a special focus on ethical theories and technical terms (ethics, bioethics, medical ethics, clinical ethics)
Animal experimentation and ethics: General remarks
Cross-faculty bridging professorship between the Institute for Textile Technology (Faculty of Mechanical Engineering) and the Helmholtz Institute for Biomedical Engineering (Faculty of Medicine) RWTH Aachen University
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Prof. Dr. Stefan Jockenhövel has a cross-faculty bridging professorship between the Institute for Textile Technology (Faculty of Mechanical Engineering) and the AME-Helmholtz Institute for Biomedical Engineering (Faculty of Medicine) at the RWTH Aachen University. This position enables him to build a bridge from the material sciences, utilizing the textile production chain, toward the development and (pre)clinical testing of innovative implants. Based on 11 years of clinical experience in cardiothoracic and vascular surgery, the focus of his research is the development of textile reinforced, tissue engineered implants, for example heart valves, vascular prostheses and vital stent structures. The key focus of Prof. Jockenhövel’s research group is the translation of innovative implants into clinical use. Therefore, the group posesses major expertise in in vitro and in vivo (pre)clinical implant testing. The sessions with Professor Jockenhövel will cover:
Fundamental aspects for the development of medical devices
Principles for the development of vital, tissue engineered implants and their in vitro evaluation
Planning and conducting preclinical studies on tissue engineered implants in the field of cardiothoracic and vascular surgery
Regulatory aspects and translation of vital implants (ATMPs) into clinical use
